Inflammation may contribute to the pathogenesis of various forms of pulmonary hypertension (PH).
Inflammation may contribute to the pathogenesis of various forms of pulmonary hypertension (PH). Recent studies in patients with idiopathic PH or PH associated with underlying diseases suggest a role for interleukin-6 (IL-6).
Methods: To determine whether endogenous IL-6 contributes to mediate hypoxic PH and lung inflammation, we studied IL-6-deficient (IL-6-/-) and wild-type (IL-6+/+) mice exposed to hypoxia for 2 weeks.
Brave Abby McDonald inspires mother Sherrie
We know that Sherrie has had her transplant now but thought i would post this in the news section cause it is a fabulous article.
Bone Marrow Cells Help Repair Damaged Lung
ScienceDaily (Jan. 27, 2009) — Thomas Waddell and colleagues, at Toronto General Research Institute, Toronto, have identified a population of mouse bone marrow cells that can contribute to repair of the injured lung.
Dr. Stuart Jamieson Named to Endowed Chair of Cardiothoracic Surgery at UC San Diego Medical Center
Jamieson’s research and therapies are known worldwide, particularly through the UC San Diego Pulmonary Thromboendarterectomy (PTE) Program. This program, largely developed by Jamieson, is foremost in the world in the successful treatment of chronic thromboembolic pulmonary hypertension, a condition requiring the complex and delicate surgical removal of scar tissue from the lungs.
FDA approves breakthrough lung imaging system [VIDEO] - USA / ISRAEL
Israeli company Deep Breeze has invented a non-invasive radiation free lung imaging system that uses Vibration Response Imaging to build up a real-time picture of the lung.
The technology, which some are calling the biggest breakthrough since ultrasound, can be used to diagnose cancer, asthma and other pulmonary diseases. Sales will begin in the US shortly.
New device could save lives of patients with lung failure - UK
It will help patients who are waiting for a lung transplant and those with severe pneumonia or other illnesses whose lungs need time to heal, Zwischenberger said.
Anticlotting Drug From Genetically Engineered Goats Is Safe Says FDA Panel - USA
An expert panel that advises the US Food and Drug Adminstration (FDA) voted that the anti-clotting drug ATryn, which is made from the milk of genetically engineered goats, is safe and effective and be approved for the treatment of people with a rare inherited disorder that makes them susceptible to life-threatening blood clots.
Cytokinetics Announces Updates Relating to Muscle Biology Research and Non-Clinical Development Programs
Smooth muscle contractility is driven by the motor protein smooth muscle myosin. A mechanochemical enzyme, smooth muscle myosin is the cytoskeletal motor that is directly responsible for converting chemical energy into mechanical force. Cytokinetics' smooth muscle contractility program is focused to the discovery and development of small molecule smooth muscle myosin inhibitors and leverages Cytokinetics' expertise in muscle function and its application to drug discovery.
Alexion drug on fast-track to approval in Japan
Alexion Pharmaceuticals Inc. said Monday its drug Soliris has been declared an orphan drug by Japanese officials, a designation that will help speed the process of getting it approved for patients in the Pacific nation.
Soliris, a drug based on an anti-inflammatory antibody called eculizumab, is Alexion's only commercial product. It is used in the United States and Europe to treat patients with paroxysmal nocturnal hemoglobinuria, or PNH, a rare and potentially fatal genetic blood disorder.